Industrialising Single Molecule Data

 
 
 

SMi is a life science company that delivers automated high-throughput single-molecule quantification

SMi’s benchtop platform offers multiomics with scalable multiplexing that allows highly sensitive detection across a wide dynamic range.

SMi was established with a vision to bring the power of single-molecule analysis to every laboratory, without the need for specialised knowledge and infrastructure. By industrialising single-molecule data at volume and speed, SMi facilitates earlier and more informed decisions to drive the future of biomedical research and in vitro diagnostics.

 
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Our Technology

 
 
 
 
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Summaries

Read more on how our technology can impact your research area

News
SMi summarises how the study and use of enzymes can be enhanced by single molecule imaging
SMi summarises how the study and use of enzymes can be enhanced by single molecule imaging

Single molecule imaging allows scientists to understand the function of enzymes with unprecedented detail and to utilise them as reagents in novel single molecule assays. Here, we explore the unique value that this offers.

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SMi summarises the potential for single molecule imaging in Ab discovery and vaccine development
SMi summarises the potential for single molecule imaging in Ab discovery and vaccine development

SMi Systems is developing a commercial analytics platform that automates single-molecule detection and analysis. Here we describe why single-molecule measurements are likely to become the go-to approach when developing novel drugs and vaccines.

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SMi reveals how it has aligned risk processes for its RUO and IVD platforms
SMi reveals how it has aligned risk processes for its RUO and IVD platforms

SMi describes the differences between the regulatory considerations for research use only (RUO) products and those destined for in vitro diagnostics (IVD) use, and consider how risk management can be simultaneously applied.

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SMi highlights the importance of advanced algorithms to detect and analyse single molecules
SMi highlights the importance of advanced algorithms to detect and analyse single molecules

SMi Systems is developing an analytics platform that utilises advanced optics and algorithms to automate detection of single molecules within a sample. We provide an overview of computational methods and why they are so important.

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SMi discusses how single molecule imaging could impact drug development
SMi discusses how single molecule imaging could impact drug development

Single molecule analysis could transform drug development. Both the speed and quality of this process will be dramatically improved when there is a commercial single molecule platform that can accurately measure drug properties.

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SMi describes the experiments that inspired development of its platform
SMi describes the experiments that inspired development of its platform

SMi Systems is developing a revolutionary benchtop instrument that probes drug interactions at single-molecule resolution. This is the story of how the groundbreaking innovation was inspired.

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SMi provides its perspective on single molecule imaging
SMi provides its perspective on single molecule imaging

Accurate detection and quantification are the cornerstones of scientific and clinical research. Only the highest quality data enables informed decisions, but achieving this can conflict with time and financial constraints.

VIEW SMI SHORTS →

Read more →
News
SMi summarises how the study and use of enzymes can be enhanced by single molecule imaging
SMi summarises how the study and use of enzymes can be enhanced by single molecule imaging

Single molecule imaging allows scientists to understand the function of enzymes with unprecedented detail and to utilise them as reagents in novel single molecule assays. Here, we explore the unique value that this offers.

VIEW PDF →

Read more →
SMi summarises the potential for single molecule imaging in Ab discovery and vaccine development
SMi summarises the potential for single molecule imaging in Ab discovery and vaccine development

SMi Systems is developing a commercial analytics platform that automates single-molecule detection and analysis. Here we describe why single-molecule measurements are likely to become the go-to approach when developing novel drugs and vaccines.

VIEW PDF →

Read more →
SMi reveals how it has aligned risk processes for its RUO and IVD platforms
SMi reveals how it has aligned risk processes for its RUO and IVD platforms

SMi describes the differences between the regulatory considerations for research use only (RUO) products and those destined for in vitro diagnostics (IVD) use, and consider how risk management can be simultaneously applied.

VIEW PDF →

Read more →
SMi highlights the importance of advanced algorithms to detect and analyse single molecules
SMi highlights the importance of advanced algorithms to detect and analyse single molecules

SMi Systems is developing an analytics platform that utilises advanced optics and algorithms to automate detection of single molecules within a sample. We provide an overview of computational methods and why they are so important.

VIEW PDF →

Read more →
SMi discusses how single molecule imaging could impact drug development
SMi discusses how single molecule imaging could impact drug development

Single molecule analysis could transform drug development. Both the speed and quality of this process will be dramatically improved when there is a commercial single molecule platform that can accurately measure drug properties.

VIEW PDF →

Read more →
SMi describes the experiments that inspired development of its platform
SMi describes the experiments that inspired development of its platform

SMi Systems is developing a revolutionary benchtop instrument that probes drug interactions at single-molecule resolution. This is the story of how the groundbreaking innovation was inspired.

VIEW SMI SHORTS →

Read more →
SMi provides its perspective on single molecule imaging
SMi provides its perspective on single molecule imaging

Accurate detection and quantification are the cornerstones of scientific and clinical research. Only the highest quality data enables informed decisions, but achieving this can conflict with time and financial constraints.

VIEW SMI SHORTS →

Read more →
 
 
 

How it works

 
 
 
 

Results

See how our technology has been used to address some important challenges

News
SMi demonstrates quantification on beads
SMi demonstrates quantification on beads

SMi’s platform can rapidly image large numbers of beads and count the particles on their surfaces.

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SMi looks at beads and planar surfaces
SMi looks at beads and planar surfaces

There are two common approaches for the rapid analysis of analytes in a liquid sample: plate assays and bead assays. SMi can image single molecules on both.

VIEW PDF →

Read more →
SMi spotlights single molecule quantification
SMi spotlights single molecule quantification

Detection, identification and quantification are cornerstones of life sciences. SMi describes how it achieves this with its unique platform.

VIEW PDF →

Read more →
SMi demonstrates sensitive protein detection
SMi demonstrates sensitive protein detection

Being able to detect analytes is a critical aspect of drug discovery and diagnosis. Here we show how single molecule counting can increase assay sensitivity.

VIEW PDF →

Read more →
SMi shows data from its array-based single molecule DNA detection
SMi shows data from its array-based single molecule DNA detection

SMi Systems is developing a commercial analytics platform that automates single-molecule detection and analysis. Here we describe why single-molecule measurements are likely to become the go-to approach when developing novel drugs and vaccines.

VIEW PDF →

Read more →
News
SMi demonstrates quantification on beads
SMi demonstrates quantification on beads

SMi’s platform can rapidly image large numbers of beads and count the particles on their surfaces.

VIEW PDF →

Read more →
SMi looks at beads and planar surfaces
SMi looks at beads and planar surfaces

There are two common approaches for the rapid analysis of analytes in a liquid sample: plate assays and bead assays. SMi can image single molecules on both.

VIEW PDF →

Read more →
SMi spotlights single molecule quantification
SMi spotlights single molecule quantification

Detection, identification and quantification are cornerstones of life sciences. SMi describes how it achieves this with its unique platform.

VIEW PDF →

Read more →
SMi demonstrates sensitive protein detection
SMi demonstrates sensitive protein detection

Being able to detect analytes is a critical aspect of drug discovery and diagnosis. Here we show how single molecule counting can increase assay sensitivity.

VIEW PDF →

Read more →
SMi shows data from its array-based single molecule DNA detection
SMi shows data from its array-based single molecule DNA detection

SMi Systems is developing a commercial analytics platform that automates single-molecule detection and analysis. Here we describe why single-molecule measurements are likely to become the go-to approach when developing novel drugs and vaccines.

VIEW PDF →

Read more →
 

Please get in touch if you want to know more

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