SMi has developed the first automated single molecule imaging platform that fits on a benchtop
Automated means that the analytical process is fast and can be performed by non-specialist operators.
Single molecule imaging means that the analysis is extremely sensitive and highly accurate.
A platform approach means that all the components – instruments, consumables and software – are integrated into a unified system that is guaranteed to perform.
Benchtop means it can be widely deployed without specialist infrastructure.
SMi has developed proprietary consumables that allow scientists to choose the analytes and probes they want to use in their tests.
This means the platform can be used for numerous applications:
Simulated or real?
One of these images is real. The other is simulated. SMi uses sophisticated simulation techniques to generate training data for our computational models. We model the behaviours of single molecules using knowledge of their fundamental biochemical and photophysical properties. The results of these models provide a toolset that accelerates assay development and provides novel insights into the underlying properties of the molecules being tested.
Brownian Motion
SMi has dedicated data scientists to model the complexity of the natural world. At the most basic level we model how Brownian Motion impacts assay efficiency, but there are many other important factors to also consider”.
Watch the video below to see what Brownian motion looks like: